How to administer: Dose titration

Gradual dose adjustments are important to optimise treatment for patients with type 2 diabetes

Gradual dose adjustments are important to optimise treatment for patients with type 2 diabetes

To facilitate gastro-intestinal tolerability of this therapy:^1,2

Starting dose Week 2 onwards Week 3 onwards

Starting dose

0.6 mg liraglutide should be administered once daily.

Week 2 onwards

After at least 1 week on 0.6 mg once daily, the dose should be increased to 1.2 mg liraglutide.

Week 3 onwards

After at least 1 week on 1.2 mg once daily, depending on clinical response, some patients may benefit from an increase to 1.8mg, although daily doses above 1.8mg are not recommended.

Combinations and monitoring

When liraglutide is added to a sulfonylurea or insulin, a dose reduction of the latter should be considered to reduce hypoglycaemia risk¹
Combination therapy with sulfonylurea is only valid for adult patients¹
Self-monitoring of blood glucose is not needed in order to adjust the dose of liraglutide,but is needed to adjust the dose of sulfonylurea and insulin, particularly when liraglutide therapy is started and
insulin is reduced¹
A stepwise approach to insulin dose reduction is recommended¹

Zegluxen^® (liraglutide) Summary of Product Characteristics.

000697557 | December 2024