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This site is intended for healthcare professionals in the UK only. Prescribing information and Adverse Event (AE) reporting details can be found in the footer.

  • Why Zegluxen®
    • Therapeutic indications
    • Clinical efficacy
    • Mechanism of action
    • Patient eligibility
  • Cost savings
  • How to Administer
    • Dose Titration
    • Storage and shelf life
    • Method of administration
  • Safety & Tolerability
    • Possible side effects
    • Special warnings and precautions for use
    • Special populations
    • Drug interactions
  • Supporting information
    • FAQs
  • Why Zegluxen®
    • Therapeutic indications
    • Clinical efficacy
    • Mechanism of action
    • Patient eligibility
  • Cost savings
  • How to Administer
    • Dose Titration
    • Storage and shelf life
    • Method of administration
  • Safety & Tolerability
    • Possible side effects
    • Special warnings and precautions for use
    • Special populations
    • Drug interactions
  • Supporting information
    • FAQs

Patient eligibility guidelines

See NICE guideline recommendations for which patients are eligible to received treatment with glucagon-like peptide-1 (GLP-1) receptor agonists

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See NICE guideline recommendations for which patients are eligible to received treatment with glucagon-like peptide-1 (GLP-1) receptor agonists

NICE recommends that Glucagon-like peptide-1 (GLP-1) receptor agonists are prescribed for adults with insufficiently controlled Type 2 diabetes (when triple therapy with metformin and 2 other oral drugs is not effective, or when metformin is contraindicated) who:1

  • Have a Body Mass Index (BMI) of 35kg/m2 or higher (adjusted accordingly for people from Black, Asian and other minority ethnic groups) and has additional psychological or medical conditions that are related to obesity1
  • Have a BMI lower than 35kg/m2 and for whom:1
    • Insulin therapy would have significant occupational implications, or
    • Weight loss could benefit other significant obesity related comorbidities

For full patient eligibility criteria and prescribing information please see the NICE or SmPC guidelines.1,2

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BMI, Body Mass Index; GLP-1 RA, glucagon-like peptide-1 receptor agonist; NICE, National Institute of Clinical Excellence; SmPC, Summary of Product Characteristics.

1. NICE Guidelines, available from: https://www.nice.org.uk/guidance/ng28. Accessed November 2024.

2. Zegluxen® (liraglutide) Summary of Product Characteristics.

000697553 | December 2024

Prescribing information can be found here

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Reporting of side effects

Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard. Adverse events should also be reported to Zentiva Pharma UK Ltd via our online form (https://www.zentiva.co.uk/contact/mi-form), by email (UKMedInfo@zentiva.com) or by telephone (0800 090 2408).

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